Circular bivalent aptamers enhance the activation of the regenerative signaling pathway for repairing liver injury <i>in vivo</i>-Reference-Cited by-同舟云学术

Circular bivalent aptamers enhance the activation of the regenerative signaling pathway for repairing liver injury in vivo

Published:2023 Issue:12 Volume:59 Page:1621-1624
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Liang Hong¹^ORCID,Yan Zhike²,Tong Yuhong²,Chen Shan¹^ORCID,Li Jingying³^ORCID,Chen Lanlan²^ORCID,Yang Huanghao²^ORCID

Affiliation:

1. College of Geography and Oceanography, Fuzhou Institute of Oceanography, Minjiang University, Fuzhou 350108, People's Republic of China

2. MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, State Key Laboratory of Photocatalysis on Energy and Environment, College of Chemistry, Fuzhou University, Fuzhou 350108, People's Republic of China

3. College of Biological Science and Engineering, Fuzhou University, Fuzhou 350108, People's Republic of China

Abstract

We developed a circular bivalent aptamer (CBA) to precisely activate membrane receptor-mediated regenerative signaling for repairing liver injury in vivo. This work expands the applications of aptamer in the field of regenerative medicine.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC06176G

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5. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair

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