Anticancer half-sandwich Ir(<scp>iii</scp>) complex and its interaction with various biomolecules and their mixtures – a case study with ascorbic acid-Reference-Cited by-同舟云学术

Anticancer half-sandwich Ir(iii) complex and its interaction with various biomolecules and their mixtures – a case study with ascorbic acid

Published:2022 Issue:15 Volume:9 Page:3758-3770
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Masaryk Lukáš¹^ORCID,Orvoš Jakub²^ORCID,Słoczyńska Karolina³^ORCID,Herchel Radovan¹^ORCID,Moncol Ján⁴^ORCID,Milde David⁵^ORCID,Halaš Petr¹^ORCID,Křikavová Radka¹^ORCID,Koczurkiewicz-Adamczyk Paulina³^ORCID,Pękala Elżbieta³^ORCID,Fischer Róbert²^ORCID,Šalitroš Ivan¹⁴^ORCID,Nemec Ivan¹^ORCID,Štarha Pavel¹^ORCID

Affiliation:

1. Department of Inorganic Chemistry, Faculty of Science, Palacky University Olomouc, 17. listopadu 12, 77146 Olomouc, Czech Republic

2. Department of Organic Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava SK-81237, Slovakia

3. Department of Pharmaceutical Biochemistry, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland

4. Department of Inorganic Chemistry, Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava, Bratislava SK-81237, Slovakia

5. Department of Analytical Chemistry, Faculty of Science, Palacký University Olomouc, 17. listopadu 12, 771 46 Olomouc, Czech Republic

Abstract

An anticancer azo bond-containing half-sandwich Ir(iii) complex oxidizes ascorbate to dehydroascorbate, and ascorbate recovers in the presence of reduced glutathione.

Funder

Agentúra na Podporu Výskumu a Vývoja

Univerzita Palackého v Olomouci

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QI/D2QI00535B

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