Bacterial susceptibility and resistance to modelin-5-Reference-Cited by-同舟云学术

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Bacterial susceptibility and resistance to modelin-5

Published:2023 Issue:42 Volume:19 Page:8247-8263
ISSN:1744-683X
Container-title:Soft Matter
language:en
Short-container-title:Soft Matter

Author:

Dennison Sarah R.¹^ORCID,Morton Leslie HG¹,Badiani Kamal²,Harris Frederick¹,Phoenix David A.³^ORCID

Affiliation:

1. School of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston PR1 2HE, UK

2. Pepceuticals Limited, 4 Feldspar Close, Warrens Park, Enderby, Leicestershire, LE19 4JS, UK

3. Office of the Vice Chancellor, London South Bank University, 103 Borough Road, London SE1 0AA, UK

Abstract

Modelin-5 (M5-NH2) killed Pseudomonas aeruginosa with a minimum lethal concentration (MLC) of 5.86 μM and strongly bound its cytoplasmic membrane (CM) with a Kd of 23.5 μM.

Funder

Biochemical Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SM/D3SM01007D

Reference172 articles.

1. J.O'Neill , 2016 . Tackling drug-resistant infections globally: final report and recommendations. https://amr-review.org/sites/default/files/160518_Final%20paper_with%20cover.pdf

2. Will 10 Million People Die a Year due to Antimicrobial Resistance by 2050?

3. Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

4. Antimicrobial Resistance in ESKAPE Pathogens

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