Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein-Reference-Cited by-同舟云学术

Electron capture dissociation and drift tube ion mobility-mass spectrometry coupled with site directed mutations provide insights into the conformational diversity of a metamorphic protein

Published:2015 Issue:16 Volume:17 Page:10538-10550
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Harvey Sophie R.¹²³⁴,Porrini Massimiliano⁵⁶⁷⁸,Tyler Robert C.⁹¹⁰¹¹¹²,MacPhee Cait E.¹³²³⁴,Volkman Brian F.⁹¹⁰¹¹¹²,Barran Perdita E.¹¹⁴¹⁵¹⁶⁴

Affiliation:

1. School of Chemistry

2. University of Edinburgh

3. Edinburgh

4. UK

5. Institut Européen de Chimie et Biologie (IECB)

6. U869 ARNA – Inserm Chimie et Biologie des Membranes et des Nano-objets (CBMN)

7. 33607 Pessac Cedex

8. France

9. Department of Biochemistry

10. Medical College of Wisconsin

11. Milwaukee

12. USA

13. School of Physics and Astronomy

14. Manchester Institute of Biotechnology

15. University of Manchester

16. Manchester

Abstract

Ion mobility mass spectrometry can be combined with data from top-down sequencing to discern adopted conformations of proteins in the absence of solvent.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CP/C4CP05136J

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2. Electrospray ion source. Another variation on the free-jet theme

3. Electrospray and Taylor-Cone theory, Dole's beam of macromolecules at last?