Real-time imaging of cell-surface proteins with antibody-based fluorogenic probes-Reference-Cited by-同舟云学术

Real-time imaging of cell-surface proteins with antibody-based fluorogenic probes

Published:2021 Issue:40 Volume:12 Page:13477-13482
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Wang Wenchao¹,Zhang Ying¹,Zhao Hong¹,Zhuang Xinlei¹,Wang Haoting¹,He Kaifeng¹²,Xu Wanting¹,Kang Yu¹^ORCID,Chen Shuqing¹,Zeng Su¹²,Qian Linghui¹²^ORCID

Affiliation:

1. Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Cancer Center, Zhejiang University, Hangzhou 310058, China

2. Hangzhou Institute of Innovative Medicine, Zhejiang University, Hangzhou 310018, China

Abstract

A modular strategy to convert commercially available antibodies into fluorogenic probes has been developed, enabling selective recognition and wash-free imaging of endogenous membrane proteins.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Zhejiang University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/SC/D1SC03065E

Reference29 articles.

1. Cell-surface proteomics for the identification of novel therapeutic targets in cancer