Robustness in glycosylation systems: effect of modified monosaccharides, acceptor decoys and azido sugars on cellular nucleotide-sugar levels and pattern of N-linked glycosylation
Author:
Affiliation:
1. Department of Chemical & Biological Engineering
2. Biomedical Engineering and Medicine
3. University at Buffalo
4. State University of New York
5. Buffalo
Abstract
Chemical perturbation studies reveal robustness in glycosylation systems, based on comparison of LC-MS/MS quantification of cellular nucleotide-sugar levels with the observed N-linked glycan patterns.
Funder
National Heart, Lung, and Blood Institute
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
Genetics,Molecular Biology,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/MO/D0MO00023J
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