Synthesis and evaluation of thieno[2,3-d]pyrimidin-4(3H)-ones as potential antitubercular agents-Reference-Cited by-同舟云学术

Synthesis and evaluation of thieno[2,3-d]pyrimidin-4(3H)-ones as potential antitubercular agents

Published:2015 Issue:12 Volume:6 Page:2209-2215
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Borate Hanumant B.¹²³⁴,Annadate Ritesh A.¹²³⁴,Vagh Sandip S.¹²³⁴,Pisal Mahesh M.¹²³⁴,Deokate Sagar B.¹²³⁴,Arkile Manisha A.⁵²³⁴,Jadhav Nandadeep J.⁵²³⁴,Nawale Laxman U.⁵²³⁴,Sarkar Dhiman⁵²³⁴

Affiliation:

1. Division of Organic Chemistry

2. CSIR-National Chemical Laboratory

3. Pune 411 008

4. India

5. Combichem Bio-resource Centre

Abstract

Thieno[2,3-d]pyrimidin-4(3H)-ones with structures 11–38 were synthesized and some of them were found to be potent inhibitors of Mycobacterium tuberculosis H37Ra and/or Mycobacterium bovis BCG and non-toxic to human cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00404G

Reference20 articles.

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