T-cell mediated anti-tumor immunity after photodynamic therapy: why does it not always work and how can we improve it?

Author:

Anzengruber Florian12345,Avci Pinar12345,de Freitas Lucas Freitas12345,Hamblin Michael R.12345

Affiliation:

1. Wellman Center for Photomedicine

2. Massachusetts General Hospital

3. Boston

4. USA

5. Department of Dermatology

Abstract

Anti-tumor PDT liberates antigens that are taken up by dendritic cells that migrate to lymph nodes, prime naïve T-cells that proliferate and return to destroy remaining tumor cells.

Funder

National Institute of Allergy and Infectious Diseases

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Springer Science and Business Media LLC

Subject

Physical and Theoretical Chemistry

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