Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

Author:

Ebada Sherif S.12345ORCID,Al-Jawabri Nariman A.56789,Youssef Fadia S.123410ORCID,El-Kashef Dina H.123410,Knedel Tim-Oliver1112134,Albohy Amgad56141516,Korinek Michal1718192021,Hwang Tsong-Long2223192021ORCID,Chen Bing-Hung1718192021,Lin Guan-Hua24252021,Lin Chia-Yi24252021,Aldalaien Sa'ed M.56789,Disi Ahmad M.26627289,Janiak Christoph1112134ORCID,Proksch Peter1234

Affiliation:

1. Institute of Pharmaceutical Biology and Biotechnology

2. Heinrich-Heine University

3. D-40225 Düsseldorf

4. Germany

5. Department of Pharmaceutical Chemistry

6. Faculty of Pharmacy

7. Mu'tah University

8. 61710 Al-Karak

9. Jordan

10. Department of Pharmacognosy

11. Institut für Anorganische Chemie und Strukturchemie

12. Heinrich-Heine-Universität

13. D-40204 Düsseldorf

14. The British University in Egypt (BUE)

15. Al-Sherouk City

16. Egypt

17. Graduate Institute of Natural Products

18. College of Pharmacy

19. Kaohsiung Medical University

20. Kaohsiung

21. Taiwan

22. Department of Biotechnology

23. College of Life Science

24. The Institute of Biomedical Sciences

25. National Sun Yat-sen University

26. Department of Basic Pharmaceutical Sciences

27. Al-Isra University

28. 11622 Amman

Abstract

On Wednesday 11th March, 2020, the world health organization (WHO) announced novel coronavirus (COVID-19, also called SARS-CoV-2) as a pandemic.

Funder

Heinrich-Heine-Universität Düsseldorf

Ministry of Science and Technology, Taiwan

Ministry of Education

Kaohsiung Medical University

Chang Gung Memorial Hospital

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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