Pd nanosheets with their surface coordinated by radioactive iodide as a high-performance theranostic nanoagent for orthotopic hepatocellular carcinoma imaging and cancer therapy

Author:

Chen Mei12345,Guo Zhide67859,Chen Qinghua101112513,Wei Jingping12345,Li Jingchao12345,Shi Changrong67859,Xu Duo67859,Zhou Dawang101112513,Zhang Xianzhong67859ORCID,Zheng Nanfeng12345ORCID

Affiliation:

1. The State Key Laboratory for Physical Chemistry of Solid Surfaces

2. Collaborative Innovation Center of Chemistry for Energy Materials

3. National & Local Joint Engineering Research Center of Preparation Technology of Nanomaterials

4. Department of Chemistry

5. Xiamen University

6. Center for Molecular Imaging and Translational Medicine

7. State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics

8. School of Public Health

9. Xiamen 361102

10. State Key Laboratory of Cellular Stress Biology

11. Innovation Center for Cell Signaling Network

12. School of Life Sciences

13. Xiamen

Abstract

We report a pH-sensitive multifunctional theranostic platform with radiolabeled Pd nanosheets through a simple mixture of ultra-small Pd nanosheets and radioisotopes utilizing the specific adsorption of 131I and 125I on their surfaces.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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