Engineering ketoreductases for the enantioselective synthesis of chiral alcohols-Reference-Cited by-同舟云学术

Engineering ketoreductases for the enantioselective synthesis of chiral alcohols

Published:2023 Issue:49 Volume:59 Page:7518-7533
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Qiao Li¹,Luo Zhiyuan¹,Chen Haomin¹,Zhang Pengfei¹^ORCID,Wang Anming¹^ORCID,Sheldon Roger A.²³^ORCID

Affiliation:

1. College of Materials, Chemistry and Chemical Engineering; Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education; Hangzhou Normal University, Zhejiang Province, Hangzhou, 311121, Zhejiang, P. R. China

2. Molecular Sciences Institute, School of Chemistry, University of the Witwatersrand, PO Wits. 2050, Johannesburg, South Africa

3. Department of Biotechnology, Section BOC, Delft University of Technology, van der Maasweg 9, 2629 HZ Delft, The Netherlands

Abstract

This review summarises the use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated enzymes, in the highly enantiospecific reduction of prochiral ketones.

Funder

National Natural Science Foundation of China

Zhejiang Provincial Ten Thousand Plan for Young Top Talents

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC01474F

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