Rational design of a water-soluble, lipid-compatible fluorescent probe for Cu(i) with sub-part-per-trillion sensitivity-Reference-Cited by-同舟云学术

Rational design of a water-soluble, lipid-compatible fluorescent probe for Cu(i) with sub-part-per-trillion sensitivity

Published:2016 Issue:2 Volume:7 Page:1468-1473
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Morgan M. T.¹²³⁴,McCallum A. M.¹²³⁴,Fahrni C. J.¹²³⁴

Affiliation:

1. School of Chemistry and Biochemistry and Petit Institute for Bioengineering and Bioscience

2. Georgia Institute of Technology

3. Atlanta

4. USA

Abstract

Knowledge-driven optimization of the ligand and fluorophore architectures yielded an ultrasensitive Cu(i)-selective fluorescent probe featuring a 180-fold fluorescence contrast and 41% quantum yield.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C5SC03643G

Reference37 articles.

1. Fluorescence imaging of metal ions implicated in diseases

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