Synthesis of novel naphthalene-heterocycle hybrids with potent antitumor, anti-inflammatory and antituberculosis activities-Reference-Cited by-同舟云学术

Synthesis of novel naphthalene-heterocycle hybrids with potent antitumor, anti-inflammatory and antituberculosis activities

Published:2020 Issue:70 Volume:10 Page:42998-43009
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Abozeid Mohamed Ahmed¹²³⁴⁵^ORCID,El-Sawi Aya Atef¹²³⁴⁵,Abdelmoteleb Mohamed⁶⁷⁸⁹¹⁰^ORCID,Awad Hanem¹¹¹²¹³¹⁴⁵^ORCID,Abdel-Aziz Marwa Mostafa¹⁵¹⁶¹⁷⁵,Hassan Abdel-Rahman Abdel-Rahman¹²³⁴⁵,Ibrahim El-Desoky El-Sayed¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Mansoura University

4. Mansoura-35516

5. Egypt

6. Food Allergy Research & Resource Program (FARRP)

7. Department of Food Science & Technology

8. University of Nebraska

9. Lincoln

10. USA

11. Department of Tanning Materials and Leather Technology

12. Chemical Industries Research Division

13. National Research Centre

14. Giza

15. The Regional Center for Mycology and Biotechnology

16. Al-Azhar University

17. Cairo 11759

Abstract

Novel naphthalene-heterocycle hybrids were synthesized via tandem reactions of 3-formylchromone with different nucleophilic reagents. Various hybrids revealed potent antitumor and anti-inflammatory as well as promising antituberculosis activities.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA08526J

Reference43 articles.

1. Naphthalene, a versatile platform in medicinal chemistry: Sky-high perspective

2. Synthesis, biological evaluation and in silico molecular docking of novel 1-hydroxy-naphthyl substituted heterocycles

3. Synthesis and Computational Analysis of New Antioxidant and Antimicrobial Angular Chromenopyrimidines

4. Synthesis, antimicrobial evaluation, and molecular docking of some new angular allylbenzochromone derivatives

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