CaO2/gelatin oxygen slow-releasing microspheres facilitate tissue engineering efficiency for the osteonecrosis of femoral head by enhancing the angiogenesis and survival of grafted bone marrow mesenchymal stem cells-Reference-Cited by-同舟云学术

CaO2/gelatin oxygen slow-releasing microspheres facilitate tissue engineering efficiency for the osteonecrosis of femoral head by enhancing the angiogenesis and survival of grafted bone marrow mesenchymal stem cells

Published:2021 Issue:8 Volume:9 Page:3005-3018
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Wang Chengqiang¹²³⁴⁵^ORCID,Xu Haixia¹²³⁴⁵,Liu Chun¹²³⁴⁵,Peng Ziyue¹²³⁴⁵,Min Ruoxing⁶³⁴⁵⁷,Zhang Zhiming¹²³⁴⁵,Li Jianjun¹²³⁴⁵,Jin Yanglei¹²³⁴⁵,Wang Yihan¹²³⁴⁵,Li Zhihao¹²³⁴⁵,Guo Jiasong¹²³⁴⁵,Zhu Lixin¹²³⁴⁵^ORCID

Affiliation:

1. Department of Spinal Surgery

2. Orthopedic Medical Center

3. Zhujiang Hospital

4. Southern Medical University

5. Guangzhou 510280

6. Department of Ultrasound Medicine

7. China

Abstract

CaO₂/gelatin microspheres can slowly release oxygen to support cell survival in extreme hypoxia condition and enhance osteogenesis and angiogenesis in the necrotic femoral head after being grafted with 3D scaffold and BMSCs.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D0BM02071K

Reference42 articles.

1. Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)

2. eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress