An inhibitor of ubiquitin conjugation and aggresome formation
Author:
Affiliation:
1. Department of Chemistry
2. Center for Molecular Innovation and Drug Discovery
3. Chemistry of Life Processes Institute
4. Northwestern University
5. Evanston
Abstract
An inhibitor of ubiquitin activating E1 enzyme inhibits ubiquitin conjugation and aggresome formation.
Funder
Northwestern University
Pew Charitable Trusts
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C5SC01351H
Reference66 articles.
1. The role of ubiquitylation in receptor endocytosis and endosomal sorting
2. Degradation of Activated Protein Kinases by Ubiquitination
3. Ubiquitination Regulates PTEN Nuclear Import and Tumor Suppression
4. C-Terminal Ubiquitination of p53 Contributes to Nuclear Export
5. The Atg8 and Atg12 ubiquitin‐like conjugation systems in macroautophagy
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