Tuning DNA–nanoparticle conjugate properties allows modulation of nuclease activity-Reference-Cited by-同舟云学术

Tuning DNA–nanoparticle conjugate properties allows modulation of nuclease activity

Published:2021 Issue:9 Volume:13 Page:4956-4970
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Hsiao Jeff C.¹²³⁴⁵^ORCID,Buryska Tomas¹²³⁴⁵^ORCID,Kim Eunjung⁶⁷⁸^ORCID,Howes Philip D.¹²³⁴⁵^ORCID,deMello Andrew J.¹²³⁴⁵^ORCID

Affiliation:

1. Institute for Chemical and Bioengineering

2. Department of Chemistry and Applied Biosciences

3. ETH Zürich

4. 8093 Zürich

5. Switzerland

6. Division of Bioengineering and Department of Bioengineering and Nano-Bioengineering

7. Incheon National University

8. Republic of Korea

Abstract

A systematic study of the interactions between nucleases and oligonucleotide-coated gold nanoparticles (spherical nucleic acids, SNAs) demonstrates that the modular units of SNAs can be leveraged to either accelerate or suppress nuclease kinetics.

Funder

Whitaker Foundation

European Commission

Ministry of Trade, Industry and Energy

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR08668A

Reference47 articles.

1. DNA nanotechnology

2. Nanoparticles and DNA – a powerful and growing functional combination in bionanotechnology

3. Functional DNA Nanostructures for Theranostic Applications

4. Functional DNA-Containing Nanomaterials: Cellular Applications in Biosensing, Imaging, and Targeted Therapy

5. Crystal engineering with DNA

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