Transplantation of a bioengineered tissue patch promotes uterine repair in the sheep

Author:

Sehic Edina12,de Miguel Gómez Lucía12,Rabe Hardis34,Thorén Emy12,Gudmundsdottir Ingigerdur12,Oltean Mihai15,Akouri Randa12,Brännström Mats126,Hellström Mats123ORCID

Affiliation:

1. Laboratory for Transplantation and Regenerative Medicine, Sahlgrenska Academy, University of Gothenburg, Kvinnokliniken, Blå stråket 6, SE-405 30, Sweden

2. Department of Obstetrics and Gynecology, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Sweden

3. Unit of Biological Function, Division Materials and Production, RISE – Research Institutes of Sweden, Box 857, SE-50115 Borås, Sweden

4. Institute of Biomedicine, Department of Infectious diseases, Sahlgrenska Academy, University of Gothenburg, SE-405 30, Sweden

5. Department of Surgery, Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, SE-413 45, Sweden

6. Stockholm IVF-EUGIN, Hammarby allé 93, 120 63 Stockholm, Sweden

Abstract

Innovative bioengineering strategies utilizing extracellular matrix (ECM) based scaffolds derived from decellularized tissue offer new prospects for restoring damaged uterine tissue.

Funder

Stiftelserna Wilhelm och Martina Lundgrens

Knut och Alice Wallenbergs Stiftelse

Stiftelsen Handlanden Hjalmar Svenssons

Adlerbertska Research Foundation

Vetenskapsrådet

Publisher

Royal Society of Chemistry (RSC)

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