Fluorescent SAM analogues for methyltransferase based DNA labeling-Reference-Cited by-同舟云学术

Fluorescent SAM analogues for methyltransferase based DNA labeling

Published:2020 Issue:22 Volume:56 Page:3317-3320
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Goyvaerts Vince¹²³⁴⁵^ORCID,Van Snick Sven¹²³⁴⁵,D'Huys Laurens¹²³⁴⁵^ORCID,Vitale Raffaele¹²³⁴⁵^ORCID,Helmer Lauer Milena¹²³⁴⁵^ORCID,Wang Su¹²³⁴⁵,Leen Volker¹²³⁴⁵,Dehaen Wim¹²³⁴⁵,Hofkens Johan¹²³⁴⁵^ORCID

Affiliation:

1. Laboratory of Molecular Imaging and Photonics

2. Department of Chemistry

3. KU Leuven

4. 3001 Leuven

5. Belgium

Abstract

In this work, the preparation of new S-adenosyl-l-methionine (SAM) analogues for sequence specific DNA labeling is evaluated. Fluorescent cofactors were synthesized and their applicability in methyltransferase based optical mapping is demonstrated.

Funder

Vlaamse regering

Horizon 2020 Framework Programme

Fonds Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/C9CC08938A

Reference38 articles.

1. Sequence-specific covalent labelling of DNA

2. DNA fluorocode: A single molecule, optical map of DNA with nanometre resolution

3. Optical mapping of DNA: Single-molecule-based methods for mapping genomes

4. Beyond sequencing: optical mapping of DNA in the age of nanotechnology and nanoscopy

5. Hairpin Peptide Motif. A New Class of Oligopeptides for Sequence-Specific Recognition in the Minor Groove of Double-Helical DNA

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