PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework-Reference-Cited by-同舟云学术

PET image-guided kidney injury theranostics enabled by a bipyramidal DNA framework

Published:2024 Issue:8 Volume:12 Page:2086-2095
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Li Pinghui¹,Huang Zhidie¹,Duan Xiaoyan²³,Wang Tao²³,Yang Shaowen⁴⁵,Jiang Dawei⁴⁵,Li Jianbo²³^ORCID

Affiliation:

1. Inner Mongolia Medical University, Hohhot 010050, China

2. Department of Nuclear Medicine, The Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, China

3. Inner Mongolia Key Laboratory of Molecular Imaging, Hohhot 010050, China

4. Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

5. Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China

Abstract

We constructed 68Ga-BDF and employed PET imaging to establish its pharmacokinetic model. BDF was eliminated from the body via the urinary system. We observed distinct imaging indicators in UUO and AKI mouse models. Furthermore, we observed the therapeutic effect of BDF on AKI.

Funder

National Natural Science Foundation of China

Education Department of Inner Mongolia Autonomous Region

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/BM/D3BM01575K

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