Alkaline phosphatase-triggered assembly of etoposide enhances its anticancer effect
Author:
Affiliation:
1. CAS Key Laboratory of Soft Matter Chemistry
2. Department of Chemistry
3. University of Science and Technology of China
4. Hefei
5. China
6. School of Life Sciences
7. Jiangsu Institute of Nuclear Medicine
8. Wuxi
Abstract
With the assistance of a hydrogelator precursor 1P, etoposide phosphate (EP) was subjected to alkaline phosphatase-triggered assembly which obviously enhanced its anticancer efficacy.
Funder
Natural Science Foundation of Jiangsu Province
Ministry of Science and Technology of the People's Republic of China
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CC/C7CC09365A
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