Synthesis and characterization of novel dimerics-triazine derivatives as potential anti-bacterial agents against MDR clinical isolates-Reference-Cited by-同舟云学术

Synthesis and characterization of novel dimerics-triazine derivatives as potential anti-bacterial agents against MDR clinical isolates

Published:2018 Issue:13 Volume:42 Page:10676-10688
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ramadan Doaa R.¹²³⁴⁵,Elbardan Aly A.¹²³⁴⁵,Bekhit Adnan A.⁶⁷³⁵⁸,El-Faham Ayman¹²³⁴⁵,Khattab Sherine N.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Alexandria University

4. Alexandria 21321

5. Egypt

6. Department of Pharmaceutical Chemistry

7. Faculty of Pharmacy

8. Cancer Nanotechnology Research Laboratory (CNRL)

Abstract

Several dimerics-triazine Schiff bases displayed more potent anti-bacterial activity compared with ampicillin trihydrate. They revealed significantly low MIC values towards the tested MDR strains and showed a high selectivity index towards antimicrobial activity againstK. pneumoniaeandMRSA1compared to mammalian cells.

Funder

Alexandria University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2018/NJ/C8NJ01483C

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