Synthesis, kinetics and cellular studies of new phenothiazine analogs as potent human-TLK inhibitors-Reference-Cited by-同舟云学术

Synthesis, kinetics and cellular studies of new phenothiazine analogs as potent human-TLK inhibitors

Published:2023 Issue:9 Volume:21 Page:1980-1991
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Johnson Delna¹,Hussain Javeena¹,Bhoir Siddhant²,Chandrasekaran Vaishali²,Sahrawat Parul¹,Hans Tanya¹,Khalil Md Imtiaz³^ORCID,De Benedetti Arrigo³^ORCID,Thiruvenkatam Vijay²,Kirubakaran Sivapriya¹^ORCID

Affiliation:

1. Discipline of Chemistry, Indian Institute of Technology, Gandhinagar, Gujarat, 382355, India

2. Discipline of Biological Engineering, Indian Institute of Technology, Gandhinagar, Gujarat, 382355, India

3. Department of Biochemistry and Molecular Biology, LSU Health Shreveport, 1501 Kings Highway, Shreveport, LA 71103, USA

Abstract

A series of phenothiazine analogues were synthesized to study the structure–activity relationship and their potency as TLK1 inhibitors for cancer therapy.

Funder

Indian Institute of Technology Gandhinagar

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB02191A

Reference34 articles.

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