Propene-bridged cyanurate tetramers decorated on carbon nanosheets with antibacterial activity: insights from molecular modeling and in vitro studies

Author:

Agrawal Omnarayan1,Sharma Hitesh Kumar2,Chaurasia Radhika1,Bakshi Gaganjyot Kaur3,Agarwal Aakanksha1ORCID,Sen Mousumi4,Mamidala Praveen5ORCID,Dey R. K.6,Chourasia Mukesh3,Mukherjee Monalisa1ORCID

Affiliation:

1. Amity Institute of Click Chemistry Research and Studies Amity University, Uttar Pradesh, Sector-125, Noida, U.P-201313, India

2. Amity Institute of Pharmacy, Amity University, Uttar Pradesh, Sector-125, Noida, U.P-201313, India

3. Center for Computational Biology and Bioinformatics, Amity Institute of Biotechnology, Amity University Uttar Pradesh, Noida 201301, India

4. Amity Institute of Applied Sciences, Amity University, Uttar Pradesh, Sector-125, Noida, U.P-201313, India

5. Laboratory of Functional Genomics, Department of Biotechnology, Telangana University, Nizamabad-503322, India

6. Department of Chemistry, Central University of Jharkhand, Ranchi-835205, Jharkhand, India

Abstract

Propene-bridged cyanurate tetramers (PBCTs) nested onto 2D nanosheets (CNHs) exhibit antibacterial activity by disrupting bacterial cell wall synthesis.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Department of Science and Technology, Ministry of Science and Technology, India

UGC-DAE Consortium for Scientific Research, University Grants Commission

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

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