Ultrasensitive detection of multiple Alzheimer's disease biomarkers by SERS-LFA

Author:

Zhan Yuanbao123,Fei Ruihua123,Lu Yu123,Wan Yu14,Wu Xuming5,Dong Jian13ORCID,Meng Dianhuai6ORCID,Ge Qinyu13ORCID,Zhao Xiangwei123ORCID

Affiliation:

1. State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China

2. Institute of Biomaterials and Medical Devices, Southeast University, Suzhou 215163, China

3. Southeast University Shenzhen Research Institute, Shenzhen 518000, China

4. Jiangsu Simcere Pharmaceutical Co., Ltd, Nanjing 210042, China

5. Nantong Fourth People's Hospital, Jiangsu 226005, China

6. Rehabilitation Medical Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China

Abstract

A lateral flow assay, based on Surface-enhanced Raman scattering nanotags (SERS-LFA), is proposed for simultaneous quantification of multiple AD biomarkers with high sensitivity.

Funder

Jiangsu Provincial Key Research and Development Program

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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