Biomimetic microcavity interfaces for a label-free capture of pathogens in the fluid bloodstream by vortical crossflow filtration-Reference-Cited by-同舟云学术

Biomimetic microcavity interfaces for a label-free capture of pathogens in the fluid bloodstream by vortical crossflow filtration

Published:2021 Issue:36 Volume:13 Page:15220-15230
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Zheng Liyuan¹²,Zheng Xiaobo³,Yuan Shanshan⁴¹⁵,Xu Weide⁴¹,Zhang Changhuan⁴¹,Zhang Xingding²,Fan Zhiyuan⁶,Wang Jilong⁴¹⁵,Wang Zheng⁷,Huang Jinhai⁸^ORCID,Deng Junjie⁴¹⁵^ORCID

Affiliation:

1. Joint Centre of Translational Medicine, Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325000, China

2. School of Medicine (Shenzhen) Sun Yat-sen University, Guangzhou 510080, China

3. School of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou 325011, China

4. Joint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China

5. Oujiang Laboratory, (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou, Zhejiang 325000, China

6. Department of Materials Science and Engineering Drexel University, Philadelphia, PA 19104, USA

7. Research Center of Blood Transfusion Medicine, Ministry of Education Key Laboratory of Laboratory Medicine, Department of Blood Transfusion, Zhejiang Provincial People's Hospital of Hangzhou Medical College, Hangzhou 310014, China

8. Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University; Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai, China

Abstract

Our study constructs a novel gill-raker like interface for label-free transport and deposit pathogens rapidly into microcavity instead of introducing active agents to binding bacteria.

Funder

National Natural Science Foundation of China

Science Fund for Distinguished Young Scholars of Zhejiang Province

Natural Science Foundation of Zhejiang Province

Wenzhou Institute of Biomaterials and Engineering

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR03350F

Reference43 articles.

1. cAMP metabolism controls caspase-11 inflammasome activation and pyroptosis in sepsis

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4. The Crisis in Antibiotic Resistance

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