Site-specific functionalization with amino, guanidinium, and imidazolyl groups enabling the activation of 10–23 DNAzyme
Author:
Affiliation:
1. State Key Laboratory of Toxicology and Medical Countermeasures
2. Beijing Institute of Pharmacology and Toxicology
3. Beijing 100850
4. China
5. School of Pharmaceutical Sciences
6. Guizhou University
Abstract
Chemical activation of 10–23 DNAzyme was realized at A9 modified with active functional groups amino, guanidinium, and imidazolyl groups.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA02226H
Reference45 articles.
1. Chemistry and Biology of Self-Cleaving Ribozymes
2. From “Cellular” RNA to “Smart” RNA: Multiple Roles of RNA in Genome Stability and Beyond
3. New Dimensions of RNA in Molecular Recognition and Catalysis
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