Rapid, highly sensitive detection of herpes simplex virus-1 using multiple antigenic peptide-coated superparamagnetic beads-Reference-Cited by-同舟云学术

Rapid, highly sensitive detection of herpes simplex virus-1 using multiple antigenic peptide-coated superparamagnetic beads

Published:2014 Issue:23 Volume:139 Page:6126-6134
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Ran Ying-Fen¹²³⁴,Fields Conor¹²³⁴,Muzard Julien¹²³⁴,Liauchuk Viktoryia¹²³⁴,Carr Michael⁵⁶³⁴,Hall William⁵⁶³⁴,Lee Gil U.¹²³⁴

Affiliation:

1. Conway Institute for Biomolecular and Biomedical Science

2. School of Chemistry and Chemical Biology

3. University College Dublin

4. Dublin 4, Ireland

5. Centre for Research on Infectious Diseases

6. School of Medicine

Abstract

We demonstrate a label free assay employing scattering to determine the aggregation state of peptide-functionalized superparamagnetic beads. HSV-1 virus at 200 virus particles per mL was detected in 30 min, demonstrating potential use in point of care testing.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/AN/C4AN00774C

Reference34 articles.

1. Herpes Simplex

2. Comparison of Light-Cycler PCR, enzyme immunoassay, and tissue culture for detection of Herpes Simplex Virus

3. Rapid Polymerase Chain Reaction Assay to Detect Herpes Simplex Virus in the Genital Tract of Women in Labor

4. A comparison of PCR with virus isolation and direct antigen detection for diagnosis and typing of genital herpes

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