Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity-Reference-Cited by-同舟云学术

Novel one-pot synthesis of a library of 2-aryloxy-1,4-naphthoquinone derivatives. Determination of antifungal and antibacterial activity

Published:2022 Issue:29 Volume:12 Page:18507-18523
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chaves-Carballo Katherine¹^ORCID,Lamoureux Guy V.¹^ORCID,Perez Alice L.¹^ORCID,Bella Cruz Alexandre²,Cechinel Filho Valdir²

Affiliation:

1. Centro de Investigaciones en Productos Naturales and Escuela de Química, Universidad de Costa Rica, San Pedro 2060, San José, Costa Rica

2. Núcleo de Investigações Químico-Farmacêuticas (NIQFAR), CCS, Universidade do Vale do Itajaí (UNIVALI), Itajaí, SC, Brazil

Abstract

The development of new antibiotics and inexpensive antifungals is an important field of research. Based on the privileged pharmacophore of lawsone, a series of phenolic ether derivatives of 1,4-naphthoquinone were synthesized easily in one step in reasonable yields.

Funder

Vicerrectoría de Investigación, Universidad de Costa Rica

Consejo Nacional para Investigaciones Científicas y Tecnológicas

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA01814D

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