Controlled release of silibinin in GelMA hydrogels inhibits inflammation by inducing M2-type macrophage polarization and promotes vascularization <i>in vitro</i>-Reference-Cited by-同舟云学术

Controlled release of silibinin in GelMA hydrogels inhibits inflammation by inducing M2-type macrophage polarization and promotes vascularization in vitro

Published:2022 Issue:21 Volume:12 Page:13192-13202
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Xu Weijian¹,Sun Yingjia¹,Wang Jia²,Wang Baixiang³,Xu Fanxing⁴,Xie Zhijian¹^ORCID,Wang Yu³^ORCID

Affiliation:

1. Department of Oral and Maxillofacial Surgery, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China

2. Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, 166 Qiutaobei Road, Shangcheng District, Hangzhou, Zhejiang, 310016, China

3. Department of Oral Implantology, Stomatology Hospital, School of Stomatology, Zhejiang University School of Medicine, Zhejiang Provincial Clinical Research Center for Oral Diseases, Key Laboratory of Oral Biomedical Research of Zhejiang Province, Cancer Center of Zhejiang University, Hangzhou 310006, China

4. Wuya College of Innovation, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China

Abstract

This study suggests that Sil-GelMA hydrogels have an anti-inflammatory effect and the potential to promote vascularization. These Sil-GelMA hydrogels might provide a promising prospect for prevention of dry sockets in the future.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA00498D

Reference49 articles.

1. Dry Socket Etiology, Diagnosis, and Clinical Treatment Techniques

2. Role of turmeric in management of alveolar osteitis (dry socket): A randomised clinical study