A smart copper(ii)-responsive binuclear gadolinium(iii) complex-based magnetic resonance imaging contrast agent

Author:

Xiao Yan-meng12345,Zhao Gui-yan12345,Fang Xin-xiu12345,Zhao Yong-xia12345,Wang Guan-hua678,Yang Wei123,Xu Jing-wei123

Affiliation:

1. State Key Laboratory of Electroanalytical Chemistry

2. Changchun Institute of Applied Chemistry

3. Changchun 130022, P. R. China

4. University of Chinese Academy of Sciences

5. Beijing, P. R. China

6. Guangdong Provincial Public Laboratory of Analysis and Testing Technology

7. Guangdong Institute of Analysis

8. Guangzhou 510070, P. R. China

Abstract

The relaxivity of the complex was modulated by Cu2+, that is, in the absence of Cu2+ the complex exhibited a relatively low relaxivity value of 6.40 mM−1 s−1, while the addition of Cu2+ triggered the relaxivity to 11.28 mM−1 s−1, an enhancement of approximately 76%.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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