Asymmetric total synthesis strategies of halichlorine and pinnaic acid-Reference-Cited by-同舟云学术

Asymmetric total synthesis strategies of halichlorine and pinnaic acid

Published:2023 Issue:48 Volume:13 Page:33754-33769
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Liu Lu¹,Jiang Minghua¹,Zhang Qingkang¹,Chen Hong¹,Zhang Yifu¹²,Zhang Jian¹²³^ORCID

Affiliation:

1. School of Pharmacy, Gansu University of Chinese Medicine, Lanzhou 730000, P. R. China

2. Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-Constructed by Gansu Province & MOE of PRC, Lanzhou 730000, P. R. China

3. Key Laboratory of Chemistry and Quality for TCM of the College of Gansu Province, Lanzhou 730000, P. R. China

Abstract

Halichlorine and pinnaic acids are structurally related to natural alkaloids isolated from different marine organisms. This review summarizes the asymmetric synthesis strategies of halichlorine and pinnaic acid using a 6-azaspiro[4.5]decane skeleton as the key intermediate.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA06955A

Reference139 articles.

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3. Synthetic Chemistry of Halichlorine and the Pinnaic Acids

4. Construction of azaspirocyclic skeletons mediated by the carbonyl of the Weinreb amide: formal total synthesis of (±)-cephalotaxine

5. Concise Synthesis of (±)-Cephalotaxine