Construction of multi-scale vascular chips and modelling of the interaction between tumours and blood vessels

Author:

Nie Jing12345,Gao Qing12345,Xie Chaoqi12345,Lv Shang12345,Qiu Jingjiang6785,Liu Yande910115,Guo Mengzi121314,Guo Rui1516175ORCID,Fu Jianzhong12345,He Yong12345ORCID

Affiliation:

1. State Key Laboratory of Fluid Power and Mechatronic Systems

2. School of Mechanical Engineering

3. Zhejiang University

4. Hangzhou 310027

5. China

6. School of Mechanics and Safety Engineering

7. Zhengzhou University

8. Zhengzhou 450001

9. School of Mechatronics & Vehicle Engineering

10. East China Jiaotong University

11. Nanchang 330013

12. McCormick School of Engineering

13. Northwestern University

14. USA

15. Department of Biomedical Engineering

16. Jinan University

17. Guangzhou 510632

Abstract

Here, we constructs a whole vascular system, from arteries and capillaries to veins with a high resolution 3D printing. A bulk breast tumor tissue with a functional vascular network was built. The interaction between tumors and vessels is investigated.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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