Naphthoquinone derivatives as potential immunomodulators: prospective for COVID-19 treatment-Reference-Cited by-同舟云学术

Naphthoquinone derivatives as potential immunomodulators: prospective for COVID-19 treatment

Published:2024 Issue:10 Volume:14 Page:6532-6541
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Moraes Vitor Tassara¹^ORCID,Caires Franco Jazon¹^ORCID,da Silva-Neto Pedro V.²^ORCID,Mendonça Jacqueline Nakau¹^ORCID,Fraga-Silva Thais F. C.³⁴^ORCID,Fontanezi Bianca Bueno⁵^ORCID,Marcato Priscyla Daniely⁵^ORCID,Deperon Bonato Vania Luiza⁴^ORCID,Sorgi Carlos Arterio²^ORCID,Beraldo Moraes Luiz Alberto²^ORCID,Clososki Giuliano Cesar¹^ORCID

Affiliation:

1. Departamento de Ciências Biomoleculares, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil

2. Departamento de Química, Faculdade de Filosofia, Ciências e Letras de Ribeirão Preto-FFCLRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-901, SP, Brazil

3. Instituto de Ciências Biológicas e da Saúde, Universidade Federal de Alagoas-UFAL, Maceió 57072-900, AL, Brazil

4. Departamento de Bioquímica e Imunologia, Faculdade de Medicina de Ribeirão Preto-FMRP, Universidade de São Paulo-USP, Ribeirão Preto 14040-900, SP, Brazil

5. Departamento de Ciências Farmacêuticas, Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo-USP, Ribeirão Preto 14040-903, SP, Brazil

Abstract

The microbial naphthoquinone 3,5,8-TMON and its derivatives showed great anti-inflammatory activity, regulating cytokines and with promising activity mitigating COVID-19 inflammatory impacts.

Funder

Fundação de Amparo à Pesquisa do Estado de São Paulo

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA08173G

Reference31 articles.

1. The non-canonical NF-κB pathway in immunity and inflammation

2. Origin and physiological roles of inflammation

3. COVID-19: Integrating the Complexity of Systemic and Pulmonary Immunopathology to Identify Biomarkers for Different Outcomes

4. The immunology and immunopathology of COVID-19

5. Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses