Fluoroarylation ofgem-difluorostyrenes through a Pd-catalysed aryl C–H bond activation cascade

Author:

Chen Lei1ORCID,Pu Jun1ORCID,Ye Peng1ORCID,Wang Shuang1,Mao Yang-Jie1ORCID,Xu Zhen-Yuan1,Lou Shao-Jie1ORCID,Xu Dan-Qian1ORCID

Affiliation:

1. Catalytic Hydrogenation Research Center, State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology, Key Laboratory of Green Pesticides and Cleaner Production Technology of Zhejiang Province, Zhejiang University of Technology, Hangzhou 310014, P. R. China

Abstract

A novel fluoroarylation of gem-difluorostyrenes with AgF and (hetero)arenes through a Pd(ii)-catalysed C(aryl)–H activation cascade was developed, constituting an efficient method to access CF3-substituted fluorenes and 1,1-diarylmethanes.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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