One-pot synthesis of quaternary pyridinium salts of lupane triterpenoids and their antimicrobial properties

Author:

Shakurova Elvira R.1,Efimova Svetlana S.2,Ostroumova Olga S.2,Parfenova Lyudmila V.1ORCID

Affiliation:

1. Institute of Petrochemistry and Catalysis, Ufa Federal Research Center, Russian Academy of Sciences, 141 Prospekt Oktyabrya, Ufa 450075, Russian Federation

2. Institute of Cytology of Russian Academy of Sciences, 4 Tikhoretsky prospect, 194064, Saint Petersburg, Russian Federation

Abstract

C30-quaternized derivatives of lupane triterpenoids (31 examples) were synthesized with a yield of 85–95% via a one-pot functionalization of a double bond under the action of organic tribromides and pyridines.

Funder

Wellcome Trust

University of Queensland

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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