Recent development of gene therapy for pancreatic cancer using non-viral nanovectors

Author:

Liu Yu1,Wu Wei1,Wang Yiyao2,Han Shisong3ORCID,Yuan Yuanyuan4,Huang Jinsheng2ORCID,Shuai Xintao3ORCID,Peng Zhao1

Affiliation:

1. Department of Medical Oncology, the First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310003, China

2. Department of Urology, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China

3. PCFM Lab of Ministry of Education, School of Materials Science and Engineering, Sun Yat-sen University, Guangzhou, 510275, China

4. School of Basic Medical Sciences, Zhejiang Chinese Medical University, Hangzhou, 310053, China

Abstract

The preclinical and clinical developments of non-viral carrier-based gene therapy for pancreatic cancer are summarized. The clinical trials discussed provide a valuable framework for translation of gene therapy research into clinical practice.

Funder

National Natural Science Foundation of China

Department of Education of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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