Cholesteryl 6-O-acyl-α-glucosides from diverse Helicobacter spp. signal through the C-type lectin receptor Mincle-Reference-Cited by-同舟云学术

Cholesteryl 6-O-acyl-α-glucosides from diverse Helicobacter spp. signal through the C-type lectin receptor Mincle

Published:2020 Issue:39 Volume:18 Page:7907-7915
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Smith Dylan G. M.¹²³⁴,Ito Emi⁵⁶⁷⁸⁹,Yamasaki Sho⁵⁶⁷⁸⁹,Williams Spencer J.¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Bio21 Molecular Science and Biotechnology Institute

2. University of Melbourne

3. Parkville

4. Australia

5. Department of Molecular Immunology

6. Immunology Frontier Research Center

7. Osaka University

8. Suita 565-0871

9. Japan

Abstract

Stereoselective α-glucosylation of cholesterol enabled synthesis of cholesteryl 6-O-acyl-glucosides from diverse Helicobacter spp. and demonstration that they signal through the innate immune receptor Mincle.

Funder

Australian Research Council

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01776K

Reference57 articles.

1. Helicobacter - species classification and identification

2. Helicobacter pyloriInfection

3. Species differentiation and identification in the genus ofHelicobacter

4. Pathogenesis of Helicobacter pylori Infection

5. Enterohepatic Helicobacter other than Helicobacter pylori

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