Highly efficient base editing in Staphylococcus aureus using an engineered CRISPR RNA-guided cytidine deaminase-Reference-Cited by-同舟云学术

Highly efficient base editing in Staphylococcus aureus using an engineered CRISPR RNA-guided cytidine deaminase

Published:2018 Issue:12 Volume:9 Page:3248-3253
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Gu Tongnian¹²³⁴,Zhao Siqi⁵⁶⁷⁸⁴,Pi Yishuang¹²³⁴,Chen Weizhong¹²³⁴,Chen Chuanyuan⁵⁶⁷⁸⁴,Liu Qian⁹¹⁰¹¹¹²¹³,Li Min⁹¹⁰¹¹¹²¹³,Han Dali⁵⁶⁷⁸⁴,Ji Quanjiang¹²³⁴^ORCID

Affiliation:

1. School of Physical Science and Technology

2. ShanghaiTech University

3. Shanghai 201210

4. China

5. Key Laboratory of Genomic and Precision Medicine

6. Beijing Institute of Genomics

7. Chinese Academy of Sciences

8. Beijing 100101

9. Department of Laboratory Medicine

10. Ren Ji Hospital

11. School of Medicine

12. Shanghai Jiao Tong University

13. Shanghai 200127

Abstract

The base editor pnCasSA-BEC enables highly efficient base editing in Staphylococcus aureus.

Funder

National Natural Science Foundation of China

Ministry of Science and Technology of the People's Republic of China

Chinese Academy of Sciences

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC00637G

Reference35 articles.

1. Staphylococcus aureusInfections

2. Staphylococcus aureus: A Well–Armed Pathogen

3. Antimicrobial resistance in gram-positive bacteria

4. Invasive Methicillin-Resistant Staphylococcus aureus Infections in the United States

5. Rapid and Efficient Genome Editing in Staphylococcus aureus by Using an Engineered CRISPR/Cas9 System

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