Facilitating Myers–Saito cyclization through acid-triggered tautomerization for the development of maleimide-based antitumor agents-Reference-Cited by-同舟云学术

Facilitating Myers–Saito cyclization through acid-triggered tautomerization for the development of maleimide-based antitumor agents

Published:2020 Issue:9 Volume:8 Page:1971-1979
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Lu Haotian¹²³⁴⁵,Ma Hailong¹²³⁴⁵,Li Baojun¹²³⁴⁵,Zhang Mengsi¹²³⁴⁵,Chen Huimin¹²³⁴⁵,Wang Yue¹²³⁴⁵,Li Xinxin¹²³⁴⁵,Ding Yun¹²³⁴⁵,Hu Aiguo¹²³⁴⁵^ORCID

Affiliation:

1. Shanghai Key Laboratory of Advanced Polymeric Materials

2. School of Materials Science and Engineering

3. East China University of Science and Technology

4. Shanghai 200237

5. China

Abstract

Enyne-allene compounds undergo Myers–Saito cyclization at physiological temperature to generate diradical intermediates that are capable of inducing DNA damage and cell death.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Shanghai Leading Academic Discipline Project

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2020/TB/C9TB02589H

Reference75 articles.

1. Enhancement of the Reactivity of Photochemically Generated Enediynes via Keto−Enol Tautomerization

2. Cancer statistics, 2014

3. Global cancer statistics, 2012

4. Cancer research: past, present and future

5. Protein–Small Molecule Interactions in Neocarzinostatin, the Prototypical Enediyne Chromoprotein Antibiotic

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Pyridazinedione-Fused Enediyne Antitumor Antibiotics;2024

2. Synthesis, Reaction Mechanism, DNA Cleavage and Antitumor Properties of Naphthoquinone‐Based Enediynes;Asian Journal of Organic Chemistry;2023-07-19

3. Acyclic enediynes fused to triazole and benzothiophene containing propargylamine moieties;Mendeleev Communications;2023-05

4. Exploration of electronic and non-linear optical properties of novel 4-Aryl-2-methylpyridine based compounds synthesized via high-yielding Pd(0) catalysed reaction;Journal of Molecular Structure;2023-02

5. Functionalized 10-Membered Aza- and Oxaenediynes through the Nicholas Reaction;Molecules;2022-09-17