Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential-Reference-Cited by-同舟云学术

Improved reaction conditions for the synthesis of new NKP-1339 derivatives and preliminary investigations on their anticancer potential

Published:2015 Issue:2 Volume:44 Page:659-668
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Kuhn P.-S.¹²³⁴⁵,Pichler V.¹²³⁴⁵,Roller A.¹²³⁴⁵,Hejl M.¹²³⁴⁵,Jakupec M. A.¹²³⁴⁵,Kandioller W.¹²³⁴⁵,Keppler B. K.¹²³⁴⁵

Affiliation:

1. Institute of Inorganic Chemistry

2. Faculty of Chemistry

3. University of Vienna

4. 1090 Vienna

5. Austria

Abstract

NKP-1339 and KP1019 derivatives were synthesized under mild reaction settings in high yields. The characterization and influence of the N-alkyl substitution on the aqueous stability, redox potentials, in vitro cytotoxicity and cellular accumulation are discussed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT01645A

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