Polyphenols as NLRP3 inflammasome modulators in cardiometabolic diseases: a review of <i>in vivo</i> studies-Reference-Cited by-同舟云学术

Polyphenols as NLRP3 inflammasome modulators in cardiometabolic diseases: a review of in vivo studies

Published:2023 Issue:21 Volume:14 Page:9534-9553
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Villalva Marisol¹²^ORCID,Martínez-García Juan José³⁴^ORCID,Jaime Laura²^ORCID,Santoyo Susana²^ORCID,Pelegrín Pablo³⁴^ORCID,Pérez-Jiménez Jara¹⁵^ORCID

Affiliation:

1. Department of Metabolism and Nutrition, Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), Madrid, Spain

2. Institute of Food Science Research (CIAL). Universidad Autónoma de Madrid (CEI UAM+CSIC), 28049, Madrid, Spain

3. Molecular Inflammation Group, University Clinical Hospital Virgen de la Arrixaca, Biomedical Research Institute of Murcia (IMIB-Pascual Parrilla), Murcia, Spain

4. Department of Biochemistry and Molecular Biology B and Immunology, Faculty of Medicine, University of Murcia, Murcia, Spain

5. CIBER of Diabetes and Associated Metabolic Disease (CIBERDEM), ISCIII, Madrid, Spain

Abstract

Steps of the NLRP3 inflammasome activation pathway where some selected polyphenols have shown a positive modulatory effect on different cardiometabolic alterations.

Funder

Ministerio de Ciencia e Innovación

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO03015F

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5. NEK7 is an essential mediator of NLRP3 activation downstream of potassium efflux

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