Catalytic generation of ortho-quinone dimethides via donor/donor rhodium carbenes

Author:

Gao Mingchun1ORCID,Ruiz Jose M.1ORCID,Jimenez Emily1ORCID,Lo Anna1ORCID,Laconsay Croix J.1ORCID,Fettinger James C.1ORCID,Tantillo Dean J.1ORCID,Shaw Jared T.1ORCID

Affiliation:

1. Department of Chemistry, University of California, One Shields Avenue, Davis, California 95616, USA

Abstract

Substrates engineered to undergo a 1,4-C–H insertion to yield benzocyclobutenes resulted in a novel elimination reaction to yield ortho-quinone dimethide (o-QDM) products that undergo Diels–Alder or hetero-Diels–Alder cycloadditions.

Funder

National Institute of General Medical Sciences

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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