Re-evaluation of the N-terminal substitution and the D-residues of teixobactin-Reference-Cited by-同舟云学术

Re-evaluation of the N-terminal substitution and the D-residues of teixobactin

Published:2016 Issue:77 Volume:6 Page:73827-73829
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Abdel Monaim Shimaa A. H.¹²³⁴⁵,Jad Yahya E.¹²³⁴⁵,Acosta Gerardo A.⁶⁷⁸⁹¹⁰,Naicker Tricia¹²³⁴⁵,Ramchuran Estelle J.¹²³⁴⁵,El-Faham Ayman¹¹¹²¹³¹⁴¹⁵,Govender Thavendran¹²³⁴⁵,Kruger Hendrik G.¹²³⁴⁵,de la Torre Beatriz G.¹²³⁴⁵,Albericio Fernando¹²³⁴⁵^ORCID

Affiliation:

1. Catalysis and Peptide Research Unit

2. School of Health Sciences

3. University of KwaZulu-Natal

4. Durban 4001

5. South Africa

6. CIBER-BBN

7. Networking Centre on Bioengineering

8. Biomaterials and Nanomedicine

9. 08028-Barcelona

10. Spain

11. Department of Chemistry

12. Faculty of Science

13. Alexandria University

14. Alexandria 21321

15. Egypt

Abstract

Teixobactin is a head to side-chain cyclic depsipeptide with a guanidino based residue within the cycle, three d-amino acids in the tail, and a N-methylated terminal residue.

Funder

South African Agency for Science and Technology Advancement

Comisión Interministerial de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA17720D

Reference12 articles.

1. Dissociation of Antimicrobial and Hemolytic Activities in Cyclic Peptide Diastereomers by Systematic Alterations in Amphipathicity

2. The Crisis in Antibiotic Resistance