Efficient chemoenzymatic synthesis of novel galacto-N-biose derivatives and their sialylated forms

Author:

Li Lei12345,Liu Yonghui5678,Li Tiehai1234,Wang Wenjun5678,Yu Zaikuan1234,Ma Cheng1234,Qu Jingyao1234,Zhao Wei5678,Chen Xi910114,Wang Peng G.1234

Affiliation:

1. Department of Chemistry and Center for Diagnostics & Therapeutics

2. Georgia State University

3. Atlanta

4. USA

5. State Key Laboratory of Medicinal Chemical Biology and College of Pharmacy

6. Nankai University

7. Tianjin 300071

8. P. R. China

9. Department of Chemistry

10. University of California, Davis

11. Davis

Abstract

Novel galacto-N-biose derivatives and their sialylated form were efficiently synthesized via one-pot two-enzyme systems starting with monosaccharides.

Funder

National Institutes of Health

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference34 articles.

1. Glycans in cancer and inflammation — potential for therapeutics and diagnostics

2. I. Brockhausen , H.Schachter and P.Stanley, in Essentials of Glycobiology, ed. A. Varki, R. D. Cummings, J. D. Esko, H. H. Freeze, P. Stanley, C. R. Bertozzi, G. W. Hart and M. E. Etzler, Cold Spring Harbor, New York, 2nd edn, 2009, ch. 9

3. R. L. Schnaar , A.Suzuki and P.Stanley, in Essentials of Glycobiology, ed. A. Varki, R. D. Cummings, J. D. Esko, H. H. Freeze, P. Stanley, C. R. Bertozzi, G. W. Hart and M. E. Etzler, New York, 2nd edn, 2009, ch. 10

4. Structure and serology of O-antigens as the basis for classification of Proteus strains

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3