Meisenheimer complexes as hidden intermediates in the aza-SNAr mechanism-Reference-Cited by-同舟云学术

Meisenheimer complexes as hidden intermediates in the aza-SNAr mechanism

Published:2020 Issue:22 Volume:18 Page:4238-4247
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ormazábal-Toledo Rodrigo¹²³⁴⁵^ORCID,Richter Sebastián⁵⁶⁷⁸⁴,Robles-Navarro Andrés⁹⁶⁷⁸⁴,Maulén Boris⁹⁶⁷⁸⁴,Matute Ricardo A.¹²³⁴¹⁰^ORCID,Gallardo-Fuentes Sebastián⁵⁶⁷⁸⁴

Affiliation:

1. Centro Integrativo de Biología y Química Aplicada (CIBQA)

2. Universidad Bernardo OHiggins

3. Santiago 8370854

4. Chile

5. Departamento de Química

6. Facultad de Ciencias

7. Universidad de Chile

8. Santiago

9. Departamento de Física

10. Division of Chemistry and Chemical Engineering

Abstract

In this work we report a computational study about the aza-S_NAr mechanism in fluorine- and chlorine-containing azines with the aim to unravel the physical factors that determine the reactivity patterns in these heterocycles towards propylamine.

Funder

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB00600A

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