Correlations between the ECD spectra and absolute configuration of bridged-ring lactones: revisiting Beecham's rule-Reference-Cited by-同舟云学术

Correlations between the ECD spectra and absolute configuration of bridged-ring lactones: revisiting Beecham's rule

Published:2021 Issue:42 Volume:19 Page:9266-9275
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zhang Jun-Yao¹,Yang Bei-Bei¹,Yang Ya-Dong¹,Gao Fan¹,Liu Wen-Qiang¹,Li Li¹^ORCID

Affiliation:

1. Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China

Abstract

We present the theoretical verification, revision and enrichment of Beecham's rule for bridged-ring lactones. This provides an alternative way to correlate experimental ECD data with stereochemistry in addition to quantum-chemical calculation.

Funder

Chinese Academy of Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB01557E

Reference66 articles.

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