A facile access to 1-substituted and unsubstituted 3-isoquinolinones <i>via</i> Mannich or Sn2 initiated cascade reactions under catalyst-free conditions-Reference-Cited by-同舟云学术

A facile access to 1-substituted and unsubstituted 3-isoquinolinones via Mannich or Sn2 initiated cascade reactions under catalyst-free conditions

Published:2023 Issue:10 Volume:13 Page:6557-6563
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Serusi Lorenzo¹,Di Mola Antonia¹,Massa Antonio¹^ORCID

Affiliation:

1. Dipartimento di Chimica e Biologia “A. Zambelli”, Università degli Studi di Salerno, Via Giovanni Paolo II, 84084 Fisciano, Italy

Abstract

The optimization of the synthesis of the starting materials in an environmentally benign manner, allowed the identification of a common intermediate useful for the synthesis of 1-substituted and C-unsubstituted 3-isoquinolinones in cascade reactions.

Funder

Ministero dell'Università e della Ricerca

Università degli Studi di Salerno

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA00378G

Reference32 articles.

1. Tandem catalysis: a taxonomy and illustrative review

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5. Base-Promoted Cascade Reactions for the Synthesis of 3,3-Dialkylated Isoindolin-1-ones and 3-Methyleneisoindolin-1-ones

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