Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication-Reference-Cited by-同舟云学术

Ratiometric two-photon fluorescent probe for in situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication

Published:2019 Issue:76 Volume:55 Page:11358-11361
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Jiang Ao¹²³⁴⁵,Chen Guang¹²³⁴⁵^ORCID,Xu Jie¹²³⁴⁵,Liu Yuxia¹²³⁴⁵^ORCID,Zhao Guanghui¹²³⁴⁵,Liu Zhenjun¹²³⁴⁵,Chen Tao¹²³⁴⁵,Li Yulin¹²³⁴⁵,James Tony D.¹²³⁴⁵^ORCID

Affiliation:

1. The Key Laboratory of Life-Organic Analysis

2. Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine

3. College of Chemistry and Chemical Engineering

4. Qufu Normal University

5. The school attached to Qufu Normal University

Abstract

A probe for imaging of mitochondrial carboxylesterase and pH has been developed for the visualization of carboxylesterase-mediated acidification in hepatoma cells and hepatic tissues during the administration of antipyretic and anti-inflammatory drugs.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Natural Science Foundation of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC05759E

Reference34 articles.

1. Neural stem cell-mediated CE/CPT-11 enzyme/prodrug therapy in transgenic mouse model of intracerebellar medulloblastoma

2. Autophagosomes form at ER–mitochondria contact sites

3. IRE1α modulates ER and mitochondria crosstalk

4. Mitochondrial fragmentation drives selective removal of deleterious mtDNA in the germline

5. Multiple dynamin family members collaborate to drive mitochondrial division

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