Co-crystal polymorphic control by nanodroplet and electrical confinement-Reference-Cited by-同舟云学术

Co-crystal polymorphic control by nanodroplet and electrical confinement

Published:2019 Issue:18 Volume:21 Page:2845-2848
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Padrela L. M.¹²³⁴^ORCID,Castro-Dominguez B.⁵⁶⁷⁸,Ziaee A.¹²³⁴,Long B.¹²³⁴,Ryan K. M.¹²³⁴^ORCID,Walker G.¹²³⁴,O'Reilly E. J.¹²³⁴^ORCID

Affiliation:

1. Synthesis and Solid State Pharmaceutical Centre (SSPC)

2. Bernal Institute University of Limerick Limerick

3. Limerick

4. Ireland

5. Chemical Engineering Department

6. University of Bath

7. BA2 7AY Bath

8. UK

Abstract

The polymorphic control of the co-crystal carbamazepine–saccharin (CBZ–SAC) metastable form II was achieved by nano-droplet confinement in tandem with droplet surface charging induced by electrospraying the precursor solution.

Funder

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CE/C9CE00060G

Reference28 articles.

1. Polymorphism − A Perspective

2. R. Hilfiker and M.von Raumer , Polymorphism in the Pharmaceutical Industry: Solid Form and Drug Development , Wiley-VCH Verlag GmbH , Weinheim , 2019

3. Concomitant Polymorphs

4. Crystallisation of Polymorphs: Thermodynamic Insight into the Role of Solvent

5. Control of crystal polymorphs by a ‘latent inductor’: crystallization of calcium carbonate in conjunction with in situ radical polymerization of sodium acrylate in aqueous solution

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