Positive and negative nano-electrospray mass spectrometry of ruthenated serum albumin supported by docking studies: an integrated approach towards defining metallodrug binding sites on proteins

Author:

Nišavić Marija12345ORCID,Janjić Goran V.6345,Hozić Amela7891011,Petković Marijana12345,Milčić Miloš K.12345,Vujčić Zoran12345,Cindrić Mario7891011ORCID

Affiliation:

1. Department of Physical Chemistry

2. “Vinča” Institute of Nuclear Sciences

3. University of Belgrade

4. 11000 Belgrade

5. Serbia

6. Institute of Chemistry, Technology and Metallurgy

7. Centre for Proteomics and Mass Spectrometry

8. Division of Molecular Medicine

9. Ruđer Bošković Institute

10. 10000 Zagreb

11. Croatia

12. Faculty of Chemistry

Abstract

Negative mode nanoLC/nano ESI MS was used for determing Ru(ii) binding sites on protein.

Funder

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

European Cooperation in Science and Technology

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

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